Product Overview & Pipeline

//Product Overview & Pipeline
Product Overview & Pipeline 2017-07-03T17:42:57+00:00

Stem Cell-Derived Islet Replacement Therapies

vc01-101

Micrograph of PEC-Encap product engraftment after three months in a patient with type 1 diabetes, displaying healthy cell morphology and early micro-architecture

ViaCyte is developing islet cell replacement therapies for insulin-requiring diabetes. Our two key products in development deploy the same active component, PEC-01 cells, but with different delivery technologies, and addressing the unmet needs of different patient groups.

PEC-Direct™ being developed for the approximately 10% of T1D patients at highest risk of acute complications and death; expected to require immune suppressive medications to protect the engrafted cells.

PEC-Encap™ being developed for all insulin-requiring diabetes patients (T1D & T2D); designed to be therapeutic without the need for long-term immunosuppressive medications.  PEC-Encap, while expected to be a second generation product approved after PEC-Direct, was the first embryonic stem cell-derived therapy for diabetes to reach the clinic – in the STEP ONE Trial (Safety, Tolerability, and Efficacy of PEC-Encap Combination Product in Type One Diabetes).

Product Pipeline

ViaCyte is the clinical‐stage sector leader focused on stem cell‐derived cell replacement therapies. We are currently the most advanced company in diabetes islet cell therapy and maintain a robust product pipeline.

Product

Dev.

Preclinical

IND

Phase I/II

PEC-Encap
(VC-01)

T1 and Insulin-requiring T2 Diabetes

Learn More

PEC-Encap Development Completed

PEC-Encap
Preclinical
Completed

PEC-Encap IND Completed

PEC-Encap
Ph I/II
Underway

PEC-Direct
(VC-02)

High-risk T1 Diabetes

Learn More

PEC-Direct Development Completed

PEC-Direct
Preclinical
Completed

PEC-Direct IND Completed

PEC-Direct
Ph I/II
Underway

VC-03

Next Generation Product for All T1 Diabetes Patients

VC-03 R&D Underway

VC-04

All T2 Diabetes

VC-04 R&D Underway

legend pipeline blue Products

 Completed

 Underway